SCHEMBL13785124

SCHEMBL13785124

Cc1cn(CC(=O)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)/c(=N\Cc2ccccc2F)n1Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F2R P25116 10/20 0.50
MAOB P27338 5/20 0.40
MAOA P21397 3/20 0.40
BCHE P06276 2/20 0.40
ACHE P22303 2/20 0.40
S1PR2 O95136 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL4336036 0.97 F2R (0.47) F2RMAOBMAOABCHEACHE
Trifluoroacetic Acid SCHEMBL4336028 0.97 F2R (0.47) F2RMAOBMAOABCHEACHE
SCHEMBL4336031 0.89 F2R (0.39) F2RMAOBMAOABCHEACHE
SCHEMBL13785122 0.85 F2R (0.54) F2RMAOBMAOABCHEACHE
Bromide SCHEMBL4346208 0.84 F2R (0.53) F2RMAOBMAOABCHEACHE
Bromide SCHEMBL4346207 0.84 F2R (0.53) F2RMAOBMAOABCHEACHE
SCHEMBL14369048 0.84 F2R (0.57) F2RMAOBMAOABCHEACHE
SCHEMBL14346288 0.79 F2R (0.69) F2RMAOBMAOABCHEACHE
Bromide SCHEMBL4347253 0.78 F2R (0.67) F2RMAOBMAOABCHEACHE
SCHEMBL14369044 0.77 F2R (0.58) F2RMAOBMAOABCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1391456-B1 2-IMINOIMIDAZOLE DERIVATIVES EISAI R&D MAN CO LTD (JP) 2009-07-22 EP disclosed
US-7304083-B2 2-iminoimidazole derivatives (2) EISAI R&D MANAGEMENT CO., LTD. (JP) 2007-12-04 US disclosed
US-7304083-B2 2-iminoimidazole derivatives (2) EISAI R&D MANAGEMENT CO., LTD. (JP) 2007-12-04 US disclosed