Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3583785 | 0.90 | USP2 (0.58) | USP2KMT2AMEN1LMNAPOLB | |
| SCHEMBL2895423 | 0.89 | USP2 (0.57) | USP2KMT2AMEN1LMNAPOLB | |
| SCHEMBL2897583 | 0.89 | USP2 (0.55) | USP2KMT2AMEN1LMNAPOLB | |
| SCHEMBL2900359 | 0.88 | KMT2A (0.60) | USP2KMT2AMEN1LMNAPOLB | |
| SCHEMBL2895356 | 0.88 | USP2 (0.54) | USP2KMT2AMEN1LMNAPOLB | |
| SCHEMBL2902339 | 0.88 | USP2 (0.56) | USP2KMT2AMEN1LMNAPOLB | |
| SCHEMBL2902443 | 0.87 | USP2 (0.54) | USP2KMT2AMEN1LMNAPOLB | |
| SCHEMBL2915582 | 0.84 | MEN1 (0.57) | USP2KMT2AMEN1LMNAPOLB | |
| SCHEMBL2897673 | 0.84 | MEN1 (0.57) | USP2KMT2AMEN1LMNAPOLB | |
| SCHEMBL2897218 | 0.83 | NAMPT (0.49) | USP2KMT2AMEN1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009086044-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITH KLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |