Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1601033 | 0.89 | SCD (0.72) | SCDDCTPP1 | |
| SCHEMBL2474018 | 0.86 | SCD (0.54) | SCDDCTPP1 | |
| SCHEMBL1377098 | 0.86 | SCD (0.84) | SCDDCTPP1 | |
| SCHEMBL1377378 | 0.84 | SCD (0.79) | SCDDCTPP1 | |
| SCHEMBL2474692 | 0.84 | SCD (0.67) | SCDDCTPP1 | |
| SCHEMBL1381346 | 0.83 | SCD (0.71) | SCDDCTPP1 | |
| SCHEMBL937531 | 0.81 | SCD (1.00) | SCDDCTPP1 | |
| SCHEMBL1378076 | 0.81 | SCD (1.00) | SCDDCTPP1 | |
| SCHEMBL1378991 | 0.81 | SCD (1.00) | SCDDCTPP1 | |
| SCHEMBL1380329 | 0.81 | SCD (0.80) | SCDDCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4808616-B2 | — | — | 2011-11-02 | — | — | JP | claimed |
| EP-1648874-B1 | PIPERAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2011-10-05 | — | — | EP | claimed |
| EP-1846035-B1 | COMBINATION THERAPY | XENON PHARMACEUTICALS INC (CA) | 2011-09-21 | — | — | EP | claimed |
| EP-1846035-B1 | COMBINATION THERAPY | XENON PHARMACEUTICALS INC (CA) | 2011-09-21 | — | — | EP | disclosed |
| US-7919484-B2 | Combination therapy | XENON PHARMACEUTICALS INC. (CA) | 2011-04-05 | — | — | US | disclosed |
| CN-101980709-A | Pyridazine derivatives and their use as therapeutic agents | XENON PHARMACEUTICALS INC | 2011-02-23 | — | — | CN | disclosed |
| CN-101669952-A | Pyridazine derivatives and their use as therapeutic agents | XENON PHARMACEUTICALS INC | 2010-03-17 | — | — | CN | disclosed |