Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1426947 | 0.91 | GCK (0.78) | GCKKCNH2 | |
| SCHEMBL2654354 | 0.89 | GCK (0.60) | GCKKCNH2 | |
| SCHEMBL1378353 | 0.87 | GCK (0.82) | GCKKCNH2 | |
| SCHEMBL2656648 | 0.86 | GCK (0.76) | GCKKCNH2 | |
| SCHEMBL1427266 | 0.86 | GCK (1.00) | GCKKCNH2 | |
| SCHEMBL1426864 | 0.86 | GCK (0.85) | GCKKCNH2 | |
| SCHEMBL1376577 | 0.86 | GCK (0.80) | GCKKCNH2 | |
| SCHEMBL2656078 | 0.85 | GCK (0.56) | GCKKCNH2 | |
| SCHEMBL1376580 | 0.85 | GCK (0.74) | GCKKCNH2 | |
| SCHEMBL1427001 | 0.85 | GCK (0.97) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4651714-B2 | — | — | 2011-03-16 | — | — | JP | claimed |
| EP-1902052-A1 | HETEROARYL BENZAMIDE DERIVATIVES FOR USE AS GLK ACTIVATORS IN THE TREATMENT OF DIABETES | AstraZeneca AB (SE) | 2008-03-26 | — | — | EP | claimed |
| WO-2007007041-A1 | HETEROARYL BENZAMIDE DERIVATIVES FOR USE AS GLK ACTIVATORS IN THE TREATMENT OF DIABETES | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | claimed |