Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.60 |
| ▸ | MGLL | Q99685 | 9/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL648663 | 1.00 | DPP4 (0.60) | DPP4MGLLDPP9MAPTMEN1 | |
| SCHEMBL1380312 | 0.83 | DPP4 (0.62) | DPP4MGLLDPP9MAPTMEN1 | |
| SCHEMBL646218 | 0.83 | DPP4 (0.62) | DPP4MGLLDPP9MAPTMEN1 | |
| SCHEMBL6507140 | 0.83 | DPP4 (0.62) | DPP4MGLLDPP9MAPTMEN1 | |
| SCHEMBL6507143 | 0.83 | DPP4 (0.62) | DPP4MGLLDPP9MAPTMEN1 | |
| SCHEMBL7534609 | 0.82 | DPP4 (0.67) | DPP4DPP9 | |
| SCHEMBL7534605 | 0.82 | DPP4 (0.67) | DPP4DPP9 | |
| SCHEMBL4703708 | 0.80 | DPP4 (0.68) | DPP4DPP9EPHX2 | |
| SCHEMBL648643 | 0.80 | DPP4 (0.68) | DPP4DPP9EPHX2 | |
| SCHEMBL4705700 | 0.79 | DPP4 (0.89) | DPP4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4712387-B2 | — | — | 2011-06-29 | — | — | JP | claimed |
| EP-1560811-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | Abbott Laboratories (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004026822-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2004-04-01 | — | — | WO | claimed |
| EP-1560811-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | Abbott Laboratories (US) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004026822-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2004-04-01 | — | — | WO | disclosed |