Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 9/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.67 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13793245 | 0.89 | NPY5R (0.69) | NPY5RADRA2AMCHR1SLC6A4MAPT | |
| SCHEMBL13793807 | 0.89 | NPY5R (0.80) | NPY5RADRA2AMCHR1SLC6A4MAPT | |
| SCHEMBL8899645 | 0.88 | NPY5R (0.69) | NPY5RADRA2AMCHR1MEN1KMT2A | |
| SCHEMBL13794023 | 0.87 | NPY5R (0.78) | NPY5RADRA2AMCHR1SLC6A4MAPT | |
| SCHEMBL13793284 | 0.87 | NPY5R (0.74) | NPY5RADRA2AMCHR1SLC6A4MAPT | |
| SCHEMBL13794355 | 0.87 | NPY5R (0.74) | NPY5RADRA2AMCHR1MEN1KMT2A | |
| SCHEMBL13793741 | 0.87 | NPY5R (0.61) | NPY5RADRA2AMCHR1MEN1KMT2A | |
| SCHEMBL13794171 | 0.86 | NPY5R (0.73) | NPY5RADRA2AMCHR1MEN1KMT2A | |
| SCHEMBL13794024 | 0.86 | NPY5R (0.73) | NPY5RADRA2AMCHR1SLC6A4MAPT | |
| SCHEMBL13793810 | 0.86 | NPY5R (0.73) | NPY5RADRA2AMCHR1SLC6A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |