Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 16/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 15/20 | 0.63 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.58 |
| ▸ | HRH1 | P35367 | 2/20 | 0.58 |
| ▸ | HTR2B | P41595 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13792882 | 0.93 | MCHR1 (0.63) | MCHR1ADRA2ANPY5RHRH1HTR2B | |
| SCHEMBL13792969 | 0.92 | MCHR1 (0.66) | MCHR1ADRA2ANPY5RHRH1HTR2B | |
| SCHEMBL13794678 | 0.90 | NPY5R (0.57) | MCHR1ADRA2ANPY5RHRH1HTR2B | |
| SCHEMBL13793649 | 0.90 | MCHR1 (0.70) | MCHR1ADRA2ANPY5RHRH1HTR2B | |
| SCHEMBL13794100 | 0.89 | MCHR1 (0.66) | MCHR1ADRA2ANPY5RHRH1HTR2B | |
| SCHEMBL13793215 | 0.88 | MCHR1 (0.70) | MCHR1ADRA2ANPY5RHRH1HTR2B | |
| SCHEMBL13794825 | 0.88 | MCHR1 (0.61) | MCHR1ADRA2ANPY5RHRH1HTR2B | |
| Hydrochloric Acid SCHEMBL3938806 | 0.88 | MCHR1 (0.69) | MCHR1ADRA2ANPY5RHRH1HTR2B | |
| Hydrochloric Acid SCHEMBL3938799 | 0.88 | MCHR1 (0.69) | MCHR1ADRA2ANPY5RHRH1HTR2B | |
| SCHEMBL13793683 | 0.87 | MCHR1 (0.60) | MCHR1ADRA2ANPY5RHRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |