Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 15/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 14/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13795465 | 0.90 | MCHR1 (0.58) | MCHR1ADRA2AHTR1AADRA1AHRH1 | |
| SCHEMBL13796526 | 0.89 | MCHR1 (0.55) | MCHR1ADRA2AGRIN2BHTR1AADRA1A | |
| SCHEMBL13795299 | 0.89 | MCHR1 (0.55) | MCHR1ADRA2AGRIN2BHTR1AADRA1A | |
| SCHEMBL13796573 | 0.89 | MCHR1 (0.55) | MCHR1ADRA2AGRIN2BHTR1AADRA1A | |
| SCHEMBL13794585 | 0.89 | MCHR1 (0.55) | MCHR1ADRA2AGRIN2BHTR1AADRA1A | |
| SCHEMBL13795668 | 0.89 | MCHR1 (0.55) | MCHR1ADRA2AGRIN2BHTR1AADRA1A | |
| SCHEMBL13796574 | 0.89 | MCHR1 (0.55) | MCHR1ADRA2AGRIN2BHTR1AADRA1A | |
| SCHEMBL13796496 | 0.89 | MCHR1 (0.55) | MCHR1ADRA2AGRIN2BHTR1AADRA1A | |
| SCHEMBL13795256 | 0.89 | MCHR1 (0.55) | MCHR1ADRA2AGRIN2BHTR1AADRA1A | |
| SCHEMBL13794751 | 0.88 | MCHR1 (0.61) | MCHR1ADRA2AHTR1AADRA1AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |