Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.65 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | AQP1 | P29972 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
| ▸ | NPY4R | P50391 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 5/20 | 0.49 |
| ▸ | ACHE | P22303 | 5/20 | 0.49 |
| ▸ | BCHE | P06276 | 4/20 | 0.49 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13796770 | 0.95 | MRGPRX1 (0.61) | MRGPRX1NPY5RSLC6A4ALDH1A1AQP1 | |
| SCHEMBL13796315 | 0.90 | NPY5R (0.52) | MRGPRX1NPY5RSLC6A4ALDH1A1AQP1 | |
| SCHEMBL13796521 | 0.90 | MRGPRX1 (0.56) | MRGPRX1NPY5RSLC6A4ALDH1A1AQP1 | |
| SCHEMBL13795833 | 0.88 | NPY5R (0.52) | MRGPRX1NPY5RSLC6A4ALDH1A1AQP1 | |
| SCHEMBL13796340 | 0.86 | NPY5R (0.51) | MRGPRX1NPY5RSLC6A4ALDH1A1AQP1 | |
| SCHEMBL13796773 | 0.86 | NPY5R (0.61) | MRGPRX1NPY5RSLC6A4ALDH1A1AQP1 | |
| SCHEMBL13796689 | 0.86 | MRGPRX1 (0.61) | MRGPRX1NPY5RSLC6A4ALDH1A1AQP1 | |
| SCHEMBL13796446 | 0.86 | NPY5R (0.60) | NPY5RSLC6A4ALDH1A1AQP1ADRA2A | |
| SCHEMBL13796342 | 0.85 | NPY5R (0.57) | MRGPRX1NPY5RSLC6A4ALDH1A1AQP1 | |
| SCHEMBL13796090 | 0.84 | NPY5R (0.51) | MRGPRX1NPY5RSLC6A4ALDH1A1AQP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |