Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 9/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.65 |
| ▸ | PAK4 | O96013 | 1/20 | 0.51 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | AQP1 | P29972 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | NPY4R | P50391 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13796758 | 0.93 | NPY5R (0.60) | NPY5RSLC6A4PAK4PAK1ALDH1A1 | |
| SCHEMBL13796660 | 0.92 | NPY5R (0.68) | NPY5RSLC6A4PAK4PAK1ALDH1A1 | |
| SCHEMBL14606717 | 0.92 | NPY5R (0.68) | NPY5RSLC6A4PAK4PAK1ALDH1A1 | |
| SCHEMBL13796759 | 0.91 | NPY5R (0.58) | NPY5RSLC6A4PAK4PAK1ALDH1A1 | |
| SCHEMBL13796343 | 0.91 | NPY5R (0.58) | NPY5RSLC6A4PAK4PAK1ALDH1A1 | |
| SCHEMBL13796433 | 0.91 | NPY5R (0.75) | NPY5RSLC6A4ALDH1A1MAPTHPGD | |
| SCHEMBL13796365 | 0.90 | NPY5R (0.54) | NPY5RSLC6A4PAK4PAK1ALDH1A1 | |
| SCHEMBL13796835 | 0.89 | NPY5R (0.63) | NPY5RSLC6A4PAK4PAK1ALDH1A1 | |
| SCHEMBL13796437 | 0.89 | NPY5R (0.68) | NPY5RSLC6A4ALDH1A1MAPTHPGD | |
| SCHEMBL13796791 | 0.89 | NPY5R (0.56) | NPY5RSLC6A4PAK4PAK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |