Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 15/20 | 0.70 |
| ▸ | NPY5R | Q15761 | 15/20 | 0.70 |
| ▸ | ADRA2A | P08913 | 14/20 | 0.70 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | PAK4 | O96013 | 1/20 | 0.46 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | AQP1 | P29972 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | NPY4R | P50391 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13796409 | 0.92 | MCHR1 (0.79) | MCHR1NPY5RADRA2ACNR1CNR2 | |
| SCHEMBL13796801 | 0.92 | MCHR1 (0.73) | MCHR1NPY5RADRA2ACNR1CNR2 | |
| SCHEMBL13795555 | 0.88 | MCHR1 (0.71) | MCHR1NPY5RADRA2ACNR1CNR2 | |
| SCHEMBL13796799 | 0.87 | MCHR1 (0.73) | MCHR1NPY5RADRA2ACNR1CNR2 | |
| SCHEMBL13795799 | 0.87 | MCHR1 (0.80) | MCHR1NPY5RADRA2AALDH1A1MAPT | |
| SCHEMBL13796791 | 0.86 | NPY5R (0.56) | MCHR1NPY5RADRA2ACNR1CNR2 | |
| SCHEMBL14606992 | 0.86 | MCHR1 (0.79) | MCHR1NPY5RADRA2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL3939624 | 0.86 | MCHR1 (0.79) | MCHR1NPY5RADRA2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL3939621 | 0.86 | MCHR1 (0.79) | MCHR1NPY5RADRA2AALDH1A1MAPT | |
| SCHEMBL13796951 | 0.86 | MCHR1 (0.79) | MCHR1NPY5RADRA2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |