Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.57 |
| ▸ | APP | P05067 | 3/20 | 0.57 |
| ▸ | ACHE | P22303 | 2/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 14/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 13/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13795135 | 0.94 | APP (0.65) | BCHEAPPACHEMCHR1ADRA2A | |
| SCHEMBL13796104 | 0.91 | MCHR1 (0.56) | BCHEAPPACHEMCHR1ADRA2A | |
| SCHEMBL13795304 | 0.90 | APP (0.60) | BCHEAPPACHEMCHR1ADRA2A | |
| SCHEMBL13796339 | 0.90 | MCHR1 (0.58) | BCHEAPPACHEMCHR1ADRA2A | |
| SCHEMBL13796132 | 0.89 | APP (0.60) | BCHEAPPACHEMCHR1ADRA2A | |
| SCHEMBL13796254 | 0.88 | APP (0.59) | BCHEAPPACHEMCHR1ADRA2A | |
| SCHEMBL13794033 | 0.87 | MCHR1 (0.53) | BCHEAPPACHEMCHR1ADRA2A | |
| SCHEMBL13795377 | 0.87 | MCHR1 (0.51) | BCHEAPPACHEMCHR1ADRA2A | |
| SCHEMBL13795395 | 0.87 | MCHR1 (0.55) | BCHEAPPACHEMCHR1ADRA2A | |
| SCHEMBL13797061 | 0.87 | APP (0.64) | BCHEAPPACHEMCHR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |