Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 13/20 | 0.72 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.72 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.52 |
| ▸ | NPY1R | P25929 | 2/20 | 0.52 |
| ▸ | AQP1 | P29972 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13796984 | 0.91 | NPY5R (0.75) | NPY5RSLC6A4HDAC3HDAC4HDAC1 | |
| SCHEMBL13796641 | 0.91 | NPY5R (0.57) | NPY5RSLC6A4ADRA2AMCHR1NPY1R | |
| SCHEMBL13796833 | 0.89 | NPY5R (0.75) | NPY5RSLC6A4HDAC3HDAC4HDAC1 | |
| SCHEMBL13795927 | 0.89 | NPY5R (0.71) | NPY5RSLC6A4HDAC3HDAC4HDAC1 | |
| SCHEMBL13796444 | 0.89 | NPY5R (0.69) | NPY5RSLC6A4HDAC3HDAC4HDAC1 | |
| SCHEMBL13796334 | 0.88 | NPY5R (0.64) | NPY5RSLC6A4ADRA2AMCHR1NPY1R | |
| SCHEMBL13796997 | 0.88 | NPY5R (0.79) | NPY5RSLC6A4HDAC3HDAC4HDAC1 | |
| SCHEMBL13796820 | 0.88 | NPY5R (0.76) | NPY5RSLC6A4HDAC3HDAC4HDAC1 | |
| SCHEMBL13796328 | 0.87 | NPY5R (0.75) | NPY5RSLC6A4HDAC3HDAC4HDAC1 | |
| SCHEMBL13796433 | 0.87 | NPY5R (0.75) | NPY5RSLC6A4HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |