Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 15/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 11/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 10/20 | 0.51 |
| ▸ | AQP1 | P29972 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | NPY4R | P50391 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14606698 | 0.92 | NPY5R (0.54) | NPY5RSLC6A4ADRA2AMCHR1AQP1 | |
| SCHEMBL13796628 | 0.91 | NPY5R (0.55) | NPY5RSLC6A4ADRA2AMCHR1AQP1 | |
| SCHEMBL13796983 | 0.90 | NPY5R (0.56) | NPY5RSLC6A4ADRA2AMCHR1AQP1 | |
| SCHEMBL13795423 | 0.90 | NPY5R (0.56) | NPY5RSLC6A4ADRA2AMCHR1AQP1 | |
| SCHEMBL13795430 | 0.90 | NPY5R (0.62) | NPY5RSLC6A4ADRA2AMCHR1AQP1 | |
| SCHEMBL13795408 | 0.89 | NPY5R (0.53) | NPY5RSLC6A4ADRA2AMCHR1AQP1 | |
| SCHEMBL13796664 | 0.89 | NPY5R (0.53) | NPY5RSLC6A4ADRA2AMCHR1AQP1 | |
| SCHEMBL13796077 | 0.89 | NPY5R (0.50) | NPY5RSLC6A4ADRA2AMCHR1AQP1 | |
| SCHEMBL13796267 | 0.88 | NPY5R (0.55) | NPY5RSLC6A4ADRA2AMCHR1AQP1 | |
| SCHEMBL13796444 | 0.88 | NPY5R (0.69) | NPY5RSLC6A4ADRA2AMCHR1AQP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |