Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 17/20 | 0.82 |
| ▸ | NPY5R | Q15761 | 17/20 | 0.82 |
| ▸ | ADRA2A | P08913 | 16/20 | 0.82 |
| ▸ | AQP1 | P29972 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | NPY4R | P50391 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13796985 | 0.92 | MCHR1 (0.80) | MCHR1NPY5RADRA2AAQP1ALDH1A1 | |
| SCHEMBL13795902 | 0.92 | MCHR1 (0.80) | MCHR1NPY5RADRA2AAQP1ALDH1A1 | |
| SCHEMBL13795799 | 0.92 | MCHR1 (0.80) | MCHR1NPY5RADRA2AAQP1ALDH1A1 | |
| SCHEMBL13795823 | 0.91 | MCHR1 (0.79) | MCHR1NPY5RADRA2AAQP1ALDH1A1 | |
| SCHEMBL14606992 | 0.91 | MCHR1 (0.79) | MCHR1NPY5RADRA2AAQP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3939624 | 0.91 | MCHR1 (0.79) | MCHR1NPY5RADRA2AAQP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3939621 | 0.91 | MCHR1 (0.79) | MCHR1NPY5RADRA2AAQP1ALDH1A1 | |
| SCHEMBL13796951 | 0.91 | MCHR1 (0.79) | MCHR1NPY5RADRA2AAQP1ALDH1A1 | |
| SCHEMBL13796409 | 0.91 | MCHR1 (0.79) | MCHR1NPY5RADRA2AAQP1ALDH1A1 | |
| SCHEMBL13795901 | 0.91 | MCHR1 (0.78) | MCHR1NPY5RADRA2AAQP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |