Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 20/20 | 0.68 |
| ▸ | TCF7L2 | Q9NQB0 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13796634 | 0.94 | CTNNB1 (0.69) | CTNNB1TCF7L2 | |
| SCHEMBL13797210 | 0.91 | CTNNB1 (0.63) | CTNNB1TCF7L2 | |
| SCHEMBL13797214 | 0.87 | CTNNB1 (0.58) | CTNNB1TCF7L2 | |
| SCHEMBL13797207 | 0.86 | CTNNB1 (0.82) | CTNNB1TCF7L2 | |
| SCHEMBL13797221 | 0.82 | CTNNB1 (0.53) | CTNNB1TCF7L2 | |
| SCHEMBL14606635 | 0.81 | CTNNB1 (0.74) | CTNNB1TCF7L2 | |
| SCHEMBL4176740 | 0.81 | CTNNB1 (1.00) | CTNNB1TCF7L2 | |
| SCHEMBL4175843 | 0.81 | CTNNB1 (1.00) | CTNNB1TCF7L2 | |
| SCHEMBL4169642 | 0.80 | CTNNB1 (1.00) | CTNNB1TCF7L2 | |
| SCHEMBL13797204 | 0.79 | CTNNB1 (0.86) | CTNNB1TCF7L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |