Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 19/20 | 0.64 |
| ▸ | TCF7L2 | Q9NQB0 | 19/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14606715 | 0.86 | CTNNB1 (0.64) | CTNNB1TCF7L2 | |
| SCHEMBL13797204 | 0.80 | CTNNB1 (0.86) | CTNNB1TCF7L2 | |
| SCHEMBL4181522 | 0.78 | CTNNB1 (1.00) | CTNNB1TCF7L2 | |
| SCHEMBL12789187 | 0.78 | PTPN1 (0.70) | PTPN1 | |
| SCHEMBL13797207 | 0.77 | CTNNB1 (0.82) | CTNNB1TCF7L2 | |
| SCHEMBL13797222 | 0.76 | CTNNB1 (0.67) | CTNNB1TCF7L2 | |
| SCHEMBL13797215 | 0.76 | CTNNB1 (0.72) | CTNNB1TCF7L2 | |
| SCHEMBL13797212 | 0.75 | CTNNB1 (0.75) | CTNNB1TCF7L2 | |
| SCHEMBL4175284 | 0.73 | CTNNB1 (1.00) | CTNNB1TCF7L2 | |
| SCHEMBL4175851 | 0.73 | CTNNB1 (1.00) | CTNNB1TCF7L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |