Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 19/20 | 0.85 |
| ▸ | ADRA2A | P08913 | 18/20 | 0.85 |
| ▸ | NPY5R | Q15761 | 14/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13794151 | 1.00 | MCHR1 (0.85) | MCHR1ADRA2ANPY5R | |
| Hydrochloric Acid SCHEMBL3939248 | 0.99 | MCHR1 (0.84) | MCHR1ADRA2ANPY5R | |
| Hydrochloric Acid SCHEMBL3939250 | 0.99 | MCHR1 (0.84) | MCHR1ADRA2ANPY5R | |
| SCHEMBL3938796 | 0.92 | MCHR1 (1.00) | MCHR1ADRA2ANPY5R | |
| SCHEMBL3938794 | 0.92 | MCHR1 (1.00) | MCHR1ADRA2ANPY5R | |
| SCHEMBL3937209 | 0.90 | MCHR1 (1.00) | MCHR1ADRA2ANPY5R | |
| SCHEMBL3937207 | 0.90 | MCHR1 (1.00) | MCHR1ADRA2ANPY5R | |
| SCHEMBL13793961 | 0.90 | MCHR1 (1.00) | MCHR1ADRA2ANPY5R | |
| Hydrochloric Acid SCHEMBL3940209 | 0.90 | MCHR1 (0.98) | MCHR1ADRA2ANPY5R | |
| Hydrochloric Acid SCHEMBL3940211 | 0.90 | MCHR1 (0.98) | MCHR1ADRA2ANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |