Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 17/20 | 0.55 |
| ▸ | PGR | P06401 | 16/20 | 0.55 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13797685 | 1.00 | AR (0.55) | ARPGRNR3C2NR3C1LMNA | |
| SCHEMBL12942779 | 1.00 | AR (0.55) | ARPGRNR3C2NR3C1LMNA | |
| SCHEMBL12942742 | 1.00 | AR (0.55) | ARPGRNR3C2NR3C1LMNA | |
| SCHEMBL12942706 | 1.00 | AR (0.55) | ARPGRNR3C2NR3C1LMNA | |
| SCHEMBL12942714 | 1.00 | AR (0.55) | ARPGRNR3C2NR3C1LMNA | |
| SCHEMBL12942708 | 0.88 | AR (0.41) | ARPGRNR3C2NR3C1LMNA | |
| SCHEMBL12942739 | 0.86 | AR (0.57) | ARPGRNR3C2 | |
| SCHEMBL12942781 | 0.86 | AR (0.57) | ARPGRNR3C2 | |
| SCHEMBL12942849 | 0.86 | AR (0.57) | ARPGRNR3C2 | |
| SCHEMBL16572779 | 0.85 | AR (0.64) | ARPGRNR3C2NR3C1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083271-A1 | 15,16-METHYLENE-17-(1'-PROPENYL)-17,3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |