Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 16/20 | 0.51 |
| ▸ | PGR | P06401 | 15/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12904866 | 1.00 | AR (0.51) | ARPGRNR3C2LMNASLC6A4 | |
| SCHEMBL13797572 | 1.00 | AR (0.51) | ARPGRNR3C2LMNASLC6A4 | |
| SCHEMBL13556655 | 0.90 | AR (0.42) | ARPGRNR3C2 | |
| SCHEMBL13557258 | 0.89 | AR (0.51) | ARPGRNR3C2LMNASLC6A4 | |
| SCHEMBL925989 | 0.89 | AR (0.50) | ARPGRNR3C2LMNASLC6A4 | |
| SCHEMBL924304 | 0.89 | AR (0.50) | ARPGRNR3C2LMNASLC6A4 | |
| SCHEMBL13372689 | 0.86 | AR (0.48) | ARPGRNR3C2LMNASLC6A4 | |
| SCHEMBL13372615 | 0.86 | AR (0.48) | ARPGRNR3C2LMNASLC6A4 | |
| SCHEMBL13557239 | 0.84 | AR (0.46) | ARPGRNR3C2LMNASLC6A4 | |
| SCHEMBL2818265 | 0.81 | AR (0.51) | ARPGRNR3C2LMNASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083271-A1 | 15,16-METHYLENE-17-(1'-PROPENYL)-17,3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |