Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 19/20 | 0.75 |
| ▸ | ADRA2A | P08913 | 16/20 | 0.75 |
| ▸ | HRH1 | P35367 | 4/20 | 0.69 |
| ▸ | HTR2B | P41595 | 4/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.69 |
| ▸ | HTR1A | P08908 | 1/20 | 0.69 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13793619 | 1.00 | MCHR1 (0.75) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL13793622 | 0.93 | MCHR1 (0.75) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL13797483 | 0.91 | MCHR1 (0.79) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL13793243 | 0.90 | MCHR1 (0.75) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL13793457 | 0.89 | MCHR1 (0.61) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL13794549 | 0.88 | MCHR1 (0.71) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL13793788 | 0.88 | MCHR1 (0.75) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL13794697 | 0.87 | MCHR1 (0.72) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL13793332 | 0.87 | MCHR1 (0.82) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL4206820 | 0.86 | MCHR1 (1.00) | MCHR1ADRA2AHRH1HTR2BADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |