Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.69 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647061 | 1.00 | DPP4 (0.69) | DPP4NOTUMDPP9DPP8CHRM4 | |
| SCHEMBL647547 | 0.87 | DPP4 (0.70) | DPP4DPP9DPP8CHRM4 | |
| SCHEMBL5475811 | 0.84 | DPP4 (0.80) | DPP4DPP9DPP8CHRM4 | |
| SCHEMBL647026 | 0.82 | DPP4 (0.57) | DPP4DPP9 | |
| SCHEMBL6260828 | 0.82 | DPP4 (0.57) | DPP4DPP9 | |
| SCHEMBL649783 | 0.80 | DPP4 (0.68) | DPP4DPP9DPP8 | |
| SCHEMBL1380045 | 0.80 | DPP4 (0.68) | DPP4DPP9DPP8 | |
| SCHEMBL648128 | 0.79 | DPP4 (0.75) | DPP4DPP9DPP8 | |
| SCHEMBL646442 | 0.79 | DPP4 (0.67) | DPP4DPP9DPP8 | |
| SCHEMBL14263090 | 0.78 | DPP4 (0.81) | DPP4DPP9DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4712387-B2 | — | — | 2011-06-29 | — | — | JP | claimed |
| EP-1560811-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | Abbott Laboratories (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004026822-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2004-04-01 | — | — | WO | claimed |
| EP-1560811-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | Abbott Laboratories (US) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004026822-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2004-04-01 | — | — | WO | disclosed |