Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 3/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3171220 | 1.00 | CAPN1 (0.43) | CAPN1TAS2R8HDAC6TACR1GFER | |
| SCHEMBL13799188 | 0.82 | CAPN1 (0.48) | CAPN1TAS2R8HDAC6TACR1GFER | |
| SCHEMBL3162010 | 0.82 | CAPN1 (0.48) | CAPN1TAS2R8HDAC6TACR1GFER | |
| SCHEMBL3026144 | 0.82 | CAPN1 (0.48) | CAPN1HDAC6TACR1GFERCES2 | |
| SCHEMBL23873935 | 0.78 | CAPN1 (0.67) | CAPN1HDAC6TACR1GFERCES2 | |
| SCHEMBL25937447 | 0.78 | CAPN1 (0.67) | CAPN1HDAC6TACR1GFERCES2 | |
| SCHEMBL13479857 | 0.76 | CAPN1 (0.42) | CAPN1TAS2R8HDAC6TACR1GFER | |
| SCHEMBL14464270 | 0.76 | CAPN1 (0.53) | CAPN1TAS2R8HDAC6TACR1GFER | |
| SCHEMBL13479919 | 0.74 | CAPN1 (0.51) | CAPN1TAS2R8HDAC6TACR1GFER | |
| SCHEMBL3165644 | 0.74 | CAPN1 (0.51) | CAPN1TAS2R8HDAC6TACR1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450301-B2 | Piperazine compounds with a herbicidal action | BASF SE (DE) | 2013-05-28 | — | — | US | disclosed |
| US-20090156553-A1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156553-A1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | DDT, CAT, CIP2A | CAPN1 579/4885TAS2R8 4694/4885HDAC6 243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.