⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10226445 | 0.80 | — | — | |
| SCHEMBL14523678 | 0.77 | — | — | |
| SCHEMBL21733098 | 0.77 | — | — | |
| SCHEMBL18211906 | 0.77 | — | — | |
| SCHEMBL24995451 | 0.75 | ATM (0.32) | — | |
| SCHEMBL18852636 | 0.75 | ATM (0.32) | — | |
| SCHEMBL24996457 | 0.73 | — | — | |
| SCHEMBL18806173 | 0.73 | — | — | |
| SCHEMBL23572267 | 0.73 | GLB1 (0.38) | — | |
| SCHEMBL5731686 | 0.72 | CHRM2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547692-B2 | Rifamycin analogs and uses thereof | ACTIVBIOTICS PHARMA, LLC (US) | 2009-06-16 | — | — | US | disclosed |
| US-20070155715-A1 | Rifamycin analogs and uses thereof | ACTIVBIOTICS, INC. (US) | 2007-07-05 | — | — | US | disclosed |
| US-20070142392-A1 | Uses of rifamycins | ACTIVBIOTICS, INC. (US) | 2007-06-21 | — | — | US | disclosed |