Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 20/20 | 0.59 |
| ▸ | ICAM1 | P05362 | 20/20 | 0.59 |
| ▸ | ITGAL | P20701 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2394671 | 0.90 | ITGAL (0.59) | ITGB2ICAM1ITGAL | |
| SCHEMBL2391011 | 0.90 | ITGAL (0.59) | ITGB2ICAM1ITGAL | |
| SCHEMBL2393575 | 0.87 | ITGB2 (0.54) | ITGB2ICAM1ITGAL | |
| SCHEMBL2392667 | 0.84 | TMEM97 (0.56) | ITGB2ICAM1ITGAL | |
| SCHEMBL2391400 | 0.83 | ITGB2 (0.73) | ITGB2ICAM1ITGAL | |
| SCHEMBL2391408 | 0.83 | ITGB2 (0.73) | ITGB2ICAM1ITGAL | |
| SCHEMBL2414625 | 0.80 | TMEM97 (0.54) | ITGB2ICAM1ITGAL | |
| SCHEMBL2414619 | 0.80 | TMEM97 (0.54) | ITGB2ICAM1ITGAL | |
| SCHEMBL2392017 | 0.79 | TMEM97 (0.57) | ITGB2ICAM1ITGAL | |
| SCHEMBL2393237 | 0.79 | TMEM97 (0.45) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070485-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-α]IMIDAZOLE-3- CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-04 | — | — | WO | disclosed |