Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 19/20 | 0.50 |
| ▸ | ITGB2 | P05107 | 18/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 18/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12310482 | 0.92 | ITGAL (0.50) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL2395026 | 0.91 | TMEM97 (0.61) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL10311749 | 0.91 | ITGAL (0.51) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL13804306 | 0.90 | TMEM97 (0.48) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL13804276 | 0.90 | ITGAL (0.50) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL13804204 | 0.89 | TMEM97 (0.49) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL13804199 | 0.88 | TMEM97 (0.49) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL12310653 | 0.87 | TMEM97 (0.46) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL13804193 | 0.86 | ITGAL (0.57) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL2396246 | 0.85 | TMEM97 (0.63) | ITGALITGB2ICAM1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070485-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-α]IMIDAZOLE-3- CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-04 | — | — | WO | disclosed |