Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 19/20 | 0.73 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 18/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 18/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2392945 | 0.92 | ITGAL (0.86) | ITGALTMEM97ITGB2ICAM1 | |
| SCHEMBL13804336 | 0.92 | ITGAL (0.69) | ITGALTMEM97ITGB2ICAM1 | |
| SCHEMBL13804334 | 0.92 | ITGAL (0.69) | ITGALTMEM97ITGB2ICAM1 | |
| SCHEMBL13804197 | 0.85 | ITGAL (0.60) | ITGALTMEM97ITGB2ICAM1 | |
| Bi 1950 SCHEMBL31454137 | 0.84 | ITGAL (1.00) | ITGALTMEM97ITGB2ICAM1 | |
| Bi 1950 SCHEMBL2392811 | 0.84 | ITGAL (1.00) | ITGALTMEM97ITGB2ICAM1 | |
| SCHEMBL12259809 | 0.84 | ITGAL (0.81) | ITGALTMEM97ITGB2ICAM1 | |
| SCHEMBL12259802 | 0.84 | ITGAL (0.67) | ITGALTMEM97ITGB2ICAM1 | |
| SCHEMBL12259800 | 0.84 | ITGAL (0.81) | ITGALTMEM97ITGB2ICAM1 | |
| SCHEMBL12259801 | 0.82 | ITGAL (0.64) | ITGALTMEM97ITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070485-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-α]IMIDAZOLE-3- CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-04 | — | — | WO | disclosed |