Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 20/20 | 0.81 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1628477 | 0.90 | PTK2 (1.00) | PTK2PTK2B | |
| SCHEMBL29853506 | 0.90 | PTK2 (1.00) | PTK2PTK2B | |
| SCHEMBL1628356 | 0.90 | PTK2 (1.00) | PTK2PTK2B | |
| SCHEMBL1627220 | 0.90 | PTK2 (0.86) | PTK2PTK2B | |
| SCHEMBL1626371 | 0.89 | PTK2 (0.78) | PTK2PTK2B | |
| SCHEMBL1626469 | 0.89 | PTK2 (1.00) | PTK2PTK2B | |
| SCHEMBL29853458 | 0.89 | PTK2 (1.00) | PTK2PTK2B | |
| SCHEMBL1626994 | 0.89 | PTK2 (1.00) | PTK2PTK2B | |
| SCHEMBL1627786 | 0.89 | PTK2 (1.00) | PTK2PTK2B | |
| SCHEMBL12998430 | 0.89 | PTK2 (0.79) | PTK2PTK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461147-B2 | Diaminopyridines for the treatment of diseases which are characterised by excessive or anomal cell proliferation | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-11 | — | — | US | disclosed |
| WO-2009071535-A1 | DIAMINOPYRIDINES FOR THE TREATMENT OF DISEASES WHICH ARE CHARACTERISED BY EXCESSIVE OR ANOMAL CELL PROLIFERATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-11 | — | — | WO | disclosed |