Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.41 |
| ▸ | RELA | Q04206 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | ACR | P10323 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13806801 | 0.94 | MAPT (0.39) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL13806791 | 0.94 | MAPT (0.39) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL13806795 | 0.92 | MAPT (0.45) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9996731 | 0.90 | NPC1 (0.46) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL10018731 | 0.90 | NPC1 (0.46) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL13390191 | 0.90 | NPC1 (0.46) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL13806796 | 0.89 | MAPT (0.41) | LMNAMAPTKMT2APLA2G4BADRB2 | |
| SCHEMBL20653120 | 0.89 | NPC1 (0.45) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL10018728 | 0.89 | NPC1 (0.45) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL13806787 | 0.88 | NPC1 (0.44) | NPC1LMNANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541071-B2 | Liquid-crystalline (METH) acrylate derivatives and composition containing them | CHISSO CORPORATION (JP) | 2009-06-02 | — | — | US | disclosed |
| US-7541071-B2 | Liquid-crystalline (METH) acrylate derivatives and composition containing them | CHISSO CORPORATION (JP) | 2009-06-02 | — | — | US | disclosed |