Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 5/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 6/20 | 0.42 |
| ▸ | GRM5 | P41594 | 4/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12720001 | 0.92 | F2R (0.49) | F2RCNR1TMEM97ABL1GRM5 | |
| SCHEMBL12720301 | 0.92 | F2R (0.47) | F2RCNR1TMEM97ABL1GRM5 | |
| SCHEMBL12720275 | 0.89 | F2R (0.43) | F2RCNR1TMEM97ABL1GRM5 | |
| SCHEMBL12720577 | 0.88 | F2R (0.51) | F2RCNR1TMEM97ABL1MGLL | |
| SCHEMBL641762 | 0.87 | CNR1 (0.58) | F2RCNR1TMEM97GRM5 | |
| SCHEMBL12720114 | 0.87 | F2R (0.51) | F2RCNR1TMEM97ABL1FAAH | |
| SCHEMBL13808423 | 0.86 | F2R (0.43) | F2RGRM5SCD5 | |
| SCHEMBL12720338 | 0.85 | GRM5 (0.38) | F2RGRM5SCD5 | |
| SCHEMBL12719999 | 0.84 | F2R (0.43) | F2RGRM5 | |
| SCHEMBL641906 | 0.83 | CNR1 (0.55) | F2RCNR1TMEM97GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009068214-A2 | HETEROARYL-SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-06-04 | — | — | WO | disclosed |