Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 20/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 16/20 | 0.63 |
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.61 |
| ▸ | HTR2B | P41595 | 2/20 | 0.61 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.60 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13797137 | 0.94 | MCHR1 (0.69) | MCHR1ADRA2AHTR1AADRA1AHTR2B | |
| SCHEMBL13793477 | 0.91 | MCHR1 (0.65) | MCHR1ADRA2AHTR1AADRA1AHTR2B | |
| SCHEMBL13797142 | 0.89 | MCHR1 (0.80) | MCHR1ADRA2AHTR1AADRA1AHTR2B | |
| SCHEMBL13794419 | 0.89 | MCHR1 (0.66) | MCHR1ADRA2AHTR1AADRA1AHTR2B | |
| SCHEMBL13808462 | 0.87 | MCHR1 (0.64) | MCHR1ADRA2AHTR1AADRA1AHTR2B | |
| SCHEMBL13795038 | 0.87 | MCHR1 (0.65) | MCHR1ADRA2AHTR1AADRA1AHTR2B | |
| SCHEMBL13797123 | 0.84 | MCHR1 (0.67) | MCHR1ADRA2AHTR1AADRA1AHTR2B | |
| SCHEMBL13794290 | 0.84 | MCHR1 (0.66) | MCHR1ADRA2AHTR1AADRA1AHTR2B | |
| SCHEMBL13797110 | 0.83 | MCHR1 (0.67) | MCHR1ADRA2AHTR1AADRA1AHTR2B | |
| SCHEMBL13797083 | 0.83 | MCHR1 (0.62) | MCHR1ADRA2AHTR1AADRA1AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |