Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 19/20 | 0.64 |
| ▸ | CXCR1 | P25024 | 10/20 | 0.64 |
| ▸ | CCR6 | P51684 | 2/20 | 0.64 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.64 |
| ▸ | CCR4 | P51679 | 1/20 | 0.64 |
| ▸ | CCR7 | P32248 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12310859 | 0.89 | CXCR2 (0.64) | CXCR2CXCR1CCR6CXCR3CCR4 | |
| SCHEMBL18556232 | 0.78 | CXCR1 (1.00) | CXCR2CXCR1CCR6CXCR3CCR4 | |
| SCHEMBL13243271 | 0.78 | CXCR2 (0.83) | CXCR2CXCR1CCR6CCR7 | |
| SCHEMBL14450193 | 0.75 | CXCR2 (0.48) | CXCR2CXCR1CCR6CXCR3CCR4 | |
| SCHEMBL13208831 | 0.74 | CXCR2 (0.79) | CXCR2CXCR1CCR6CCR7 | |
| SCHEMBL13207901 | 0.72 | CXCR2 (0.62) | CXCR2CXCR1CCR6CCR7 | |
| SCHEMBL12572429 | 0.69 | CXCR2 (0.64) | CXCR2CXCR1 | |
| SCHEMBL12262972 | 0.68 | CXCR2 (1.00) | CXCR2CXCR1CCR6CCR7 | |
| SCHEMBL12573315 | 0.68 | CXCR2 (0.85) | CXCR2CXCR1CCR6CCR7 | |
| SCHEMBL14100687 | 0.68 | CXCR2 (0.44) | CXCR2CXCR1CCR6CXCR3CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009073683-A2 | METHODS OF TREATING COPD | SCHERING CORPORATION (US) | 2009-06-11 | — | — | WO | disclosed |