Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952800 | 0.94 | TSHR (0.40) | TSHRCA1CA2CA7ALDH1A1 | |
| SCHEMBL1862658 | 0.89 | TSHR (0.37) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL6338030 | 0.88 | TSHR (0.47) | TSHRCA1CA2CA7ALDH1A1 | |
| SCHEMBL26754610 | 0.86 | TSHR (0.35) | TSHRALDH1A1THRB | |
| SCHEMBL26754597 | 0.86 | TSHR (0.35) | TSHRCA1CA2CA7THRB | |
| SCHEMBL13449717 | 0.85 | CA1 (0.38) | CA1CA2CA7PLA2G2CTDP1 | |
| SCHEMBL14546264 | 0.85 | TSHR (0.47) | TSHRALDH1A1THRB | |
| SCHEMBL15494302 | 0.84 | TSHR (0.44) | TSHRCA1CA2CA7ALDH1A1 | |
| SCHEMBL12113819 | 0.84 | TSHR (0.33) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL22160320 | 0.82 | CYP1A2 (0.36) | TSHRCA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1386924-B1 | MONOMER, POLYMER, AND OCULAR LENS AND CONTACT LENS EACH OBTAINED THEREFROM | JOHNSON & JOHNSON VISION CARE (US) | 2009-06-10 | — | — | EP | disclosed |