Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2208634 | 0.95 | HRH3 (0.54) | HRH3 | |
| SCHEMBL2211506 | 0.87 | HRH3 (0.52) | HRH3CYP2D6 | |
| SCHEMBL1382652 | 0.84 | HRH3 (0.68) | HRH3 | |
| SCHEMBL1381236 | 0.83 | HRH3 (0.62) | HRH3CYP2D6 | |
| SCHEMBL2206407 | 0.82 | HRH3 (0.47) | HRH3CYP2D6 | |
| SCHEMBL1380898 | 0.81 | HRH3 (0.66) | HRH3CYP2D6 | |
| SCHEMBL1379003 | 0.79 | HRH3 (0.62) | HRH3 | |
| SCHEMBL1380776 | 0.79 | HRH3 (0.69) | HRH3 | |
| SCHEMBL1377780 | 0.79 | HRH3 (0.60) | HRH3 | |
| SCHEMBL2212606 | 0.79 | HRH3 (0.77) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805166-B1 | QUINOLINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2011-07-27 | — | — | EP | claimed |
| JP-4660553-B2 | — | — | 2011-03-30 | — | — | JP | claimed |
| EP-1805166-B1 | QUINOLINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2011-07-27 | — | — | EP | disclosed |