Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 11/20 | 0.57 |
| ▸ | ITGAV | P06756 | 4/20 | 0.57 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.53 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.53 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.52 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.47 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12341856 | 0.92 | ITGB1 (0.55) | ITGB1ITGAVITGA4ITGB7ITGA5 | |
| SCHEMBL16327372 | 0.92 | ITGB1 (0.60) | ITGB1ITGAVITGA4ITGB7ITGA5 | |
| SCHEMBL3857050 | 0.86 | ITGB1 (0.60) | ITGB1ITGAVITGA4ITGB7ITGA5 | |
| SCHEMBL17823300 | 0.86 | ITGB1 (0.61) | ITGB1ITGAVITGA4ITGB7ITGA5 | |
| SCHEMBL19661357 | 0.86 | ITGB1 (0.61) | ITGB1ITGAVITGA4ITGB7ITGA5 | |
| SCHEMBL19639220 | 0.86 | ITGB1 (0.61) | ITGB1ITGAVITGA4ITGB7ITGA5 | |
| SCHEMBL19660968 | 0.86 | ITGB1 (0.61) | ITGB1ITGAVITGA4ITGB7ITGA5 | |
| SCHEMBL19660966 | 0.86 | ITGB1 (0.61) | ITGB1ITGAVITGA4ITGB7ITGA5 | |
| SCHEMBL19661289 | 0.80 | ITGB1 (0.52) | ITGB1ITGAVITGA4ITGB7ITGA5 | |
| SCHEMBL19661288 | 0.80 | ITGB1 (0.52) | ITGB1ITGAVITGA4ITGB7ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009075806-A1 | METHODS AND COMPOSITIONS FOR TREATING LIQUID TUMORS | ELAN PHARMACEUTICALS, INC. (US) | 2009-06-18 | — | — | WO | disclosed |