Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 10/20 | 0.44 |
| ▸ | PPARA | Q07869 | 10/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4336800 | 1.00 | KMT2A (0.50) | KMT2ASMN1; SMN2MRGPRX4MEN1HTT | |
| SCHEMBL4336806 | 1.00 | KMT2A (0.50) | KMT2ASMN1; SMN2MRGPRX4MEN1HTT | |
| SCHEMBL6651835 | 0.92 | PPARG (0.54) | KMT2AMRGPRX4MEN1PPARGPPARA | |
| SCHEMBL4329927 | 0.92 | PPARG (0.54) | KMT2AMRGPRX4MEN1PPARGPPARA | |
| SCHEMBL4336962 | 0.92 | PPARG (0.54) | KMT2AMRGPRX4MEN1PPARGPPARA | |
| SCHEMBL4332358 | 0.91 | SMN1; SMN2 (0.44) | KMT2ASMN1; SMN2MEN1PPARGPPARA | |
| SCHEMBL4335028 | 0.89 | PPARG (0.56) | PPARGPPARAPPARD | |
| SCHEMBL4335023 | 0.89 | PPARG (0.56) | PPARGPPARAPPARD | |
| SCHEMBL4336067 | 0.89 | PPARG (0.56) | PPARGPPARAPPARD | |
| SCHEMBL4327605 | 0.89 | PPARG (0.55) | KMT2AMEN1PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |