Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | IL1B | P01584 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19888380 | 0.80 | EPHX1 (1.00) | EPHX1KDM4ECTSLCTSBCTSK | |
| SCHEMBL21229787 | 0.80 | EPHX1 (1.00) | EPHX1KDM4ECTSLCTSBCTSK | |
| SCHEMBL19888379 | 0.80 | EPHX1 (1.00) | EPHX1KDM4ECTSLCTSBCTSK | |
| SCHEMBL24383485 | 0.80 | EPHX1 (1.00) | EPHX1KDM4ECTSLCTSBCTSK | |
| SCHEMBL21229885 | 0.80 | EPHX1 (1.00) | EPHX1KDM4ECTSLCTSBCTSK | |
| SCHEMBL24029511 | 0.80 | EPHX1 (1.00) | EPHX1KDM4ECTSLCTSBCTSK | |
| SCHEMBL21229887 | 0.80 | EPHX1 (1.00) | EPHX1KDM4ECTSLCTSBCTSK | |
| SCHEMBL21229786 | 0.80 | EPHX1 (1.00) | EPHX1KDM4ECTSLCTSBCTSK | |
| SCHEMBL21107147 | 0.80 | EPHX1 (1.00) | EPHX1KDM4ECTSLCTSBCTSK | |
| SCHEMBL19888402 | 0.80 | EPHX1 (1.00) | EPHX1KDM4ECTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740591-B1 | 6,6-BICYCLIC RING SUBSTITUTED HETEROBICYCLIC PROTEIN KINASE INHIBITORS | OSI PHARM INC (US) | 2009-06-17 | — | — | EP | disclosed |