Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 11/20 | 0.56 |
| ▸ | P2RX1 | P51575 | 6/20 | 0.56 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.48 |
| ▸ | CHUK | O15111 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MYLK | Q15746 | 1/20 | 0.48 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.48 |
| ▸ | HSPH1 | Q92598 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812831 | 0.92 | TMPRSS4 (0.56) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812821 | 0.92 | TMPRSS4 (0.55) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812706 | 0.87 | MEN1 (0.52) | TMPRSS4P2RX1P2RX4P2RX7LMNA | |
| SCHEMBL13812630 | 0.87 | TMPRSS4 (0.58) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812705 | 0.86 | TMPRSS4 (0.61) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812710 | 0.86 | TMPRSS4 (0.52) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812690 | 0.84 | TMPRSS4 (0.55) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812823 | 0.84 | TMPRSS4 (0.52) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812688 | 0.83 | TMPRSS4 (0.53) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812708 | 0.83 | TMPRSS4 (0.53) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |