Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.56 |
| ▸ | HTR2B | P41595 | 3/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882597 | 0.83 | CYP2C9 (0.57) | HTR2CSLC6A4HTR2BCYP1A2CYP3A4 | |
| SCHEMBL20535690 | 0.79 | NPC1 (0.49) | HTR2CSLC6A4HTR2BHTR6NPC1 | |
| SCHEMBL9074689 | 0.78 | MEN1 (0.54) | HTR2CSLC6A4HTR2BHTR6HTT | |
| SCHEMBL15243706 | 0.78 | MRGPRX4 (0.57) | CYP1A2CYP3A4CYP2C9CYP2C19NPC1 | |
| SCHEMBL11360859 | 0.77 | NPC1 (0.56) | HTR2CSLC6A4HTR2BHTR6NPC1 | |
| SCHEMBL27689470 | 0.77 | HTR2C (0.52) | HTR2CSLC6A4HTR2BHTR6 | |
| SCHEMBL9077745 | 0.77 | HTR2C (0.52) | HTR2CSLC6A4HTR2BHTR6 | |
| Hydrochloric Acid SCHEMBL11354651 | 0.76 | NPC1 (0.54) | HTR2CSLC6A4HTR2BHTR6NPC1 | |
| SCHEMBL12505493 | 0.76 | MAPT (0.49) | CYP1A2CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL14194196 | 0.76 | MAPT (0.49) | HTR2CHTR2BCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |