Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 16/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13813975 | 0.85 | CCNC (0.47) | PDGFRBKITFLT3 | |
| SCHEMBL13814894 | 0.84 | MAOB (0.51) | ACACBPDGFRBKITFLT3 | |
| SCHEMBL4202933 | 0.80 | KIT (0.47) | ACACBPDGFRBKITFLT3 | |
| SCHEMBL4189877 | 0.80 | NR2F2 (0.49) | ACACBPDGFRBKITFLT3 | |
| SCHEMBL4965480 | 0.78 | PDGFRB (0.67) | PDGFRBKITFLT3 | |
| SCHEMBL4184815 | 0.75 | NR2F2 (0.53) | PDGFRBKITFLT3 | |
| SCHEMBL4198431 | 0.75 | KIT (0.52) | PDGFRBKITFLT3 | |
| SCHEMBL4965895 | 0.73 | FLT3 (0.57) | PDGFRBKITFLT3 | |
| SCHEMBL14599436 | 0.73 | PDGFRB (0.49) | ACACBPDGFRBFLT3 | |
| SCHEMBL13814093 | 0.73 | AKT1 (0.48) | KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143378-A1 | THIENOPYRIMIDINE AND THIENOPYRIDINE KINASE MODULATORS | GAUL MICHAEL DAVID | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143378-A1 | THIENOPYRIMIDINE AND THIENOPYRIDINE KINASE MODULATORS | FLT3, TYMP, CDK2 | ACACB 2729/4885PDGFRB 38/4885KIT 92/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.