Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | MERTK | Q12866 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11991646 | 0.91 | DHODH (0.33) | DHODH | |
| SCHEMBL12911173 | 0.86 | GPR183 (0.32) | — | |
| SCHEMBL11991617 | 0.79 | DHODH (0.34) | DHODH | |
| SCHEMBL11991504 | 0.77 | DHODH (0.32) | DHODH | |
| SCHEMBL11991645 | 0.76 | — | — | |
| SCHEMBL11991527 | 0.76 | PTGER1 (0.31) | — | |
| SCHEMBL11991492 | 0.72 | DHODH (0.32) | DHODH | |
| SCHEMBL11991505 | 0.71 | FLT1 (0.31) | — | |
| SCHEMBL15267346 | 0.71 | SCN9A (0.30) | — | |
| SCHEMBL11991526 | 0.70 | HSD17B10 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009076747-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-25 | — | — | WO | disclosed |