Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.62 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.49 |
| ▸ | ATF4 | P18848 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1381004 | 0.79 | HRH3 (0.65) | HRH3SCN9AATF4AVPR1B | |
| SCHEMBL1379003 | 0.78 | HRH3 (0.62) | HRH3 | |
| SCHEMBL2208642 | 0.78 | HRH3 (0.78) | HRH3SCN9APOLBMAPT | |
| SCHEMBL1381470 | 0.78 | HRH3 (0.63) | HRH3SCN9AATF4 | |
| SCHEMBL2212118 | 0.78 | HRH3 (0.71) | HRH3SCN9AMAOB | |
| SCHEMBL2210534 | 0.78 | HRH3 (0.60) | HRH3SCN9AATF4MAOBPOLB | |
| SCHEMBL2209047 | 0.77 | HRH3 (0.56) | HRH3SCN9A | |
| SCHEMBL2208663 | 0.77 | HRH3 (0.83) | HRH3SCN9A | |
| SCHEMBL1379269 | 0.77 | HRH3 (0.64) | HRH3SCN9AATF4MAOBPOLB | |
| SCHEMBL2210587 | 0.77 | HRH3 (1.00) | HRH3SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4660553-B2 | — | — | 2011-03-30 | — | — | JP | claimed |
| EP-1805166-B1 | QUINOLINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2011-07-27 | — | — | EP | disclosed |