Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 20/20 | 0.79 |
| ▸ | ICAM1 | P05362 | 20/20 | 0.79 |
| ▸ | ITGAL | P20701 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13817170 | 0.93 | ITGB2 (0.77) | ITGB2ICAM1ITGAL | |
| SCHEMBL14019343 | 0.89 | ITGB2 (0.81) | ITGB2ICAM1ITGAL | |
| SCHEMBL13817322 | 0.89 | ITGB2 (0.80) | ITGB2ICAM1ITGAL | |
| SCHEMBL4018228 | 0.88 | ITGB2 (1.00) | ITGB2ICAM1ITGAL | |
| SCHEMBL13817247 | 0.88 | ITGB2 (1.00) | ITGB2ICAM1ITGAL | |
| SCHEMBL4018223 | 0.88 | ITGB2 (1.00) | ITGB2ICAM1ITGAL | |
| SCHEMBL13817090 | 0.86 | ITGB2 (0.77) | ITGB2ICAM1ITGAL | |
| SCHEMBL13817197 | 0.86 | ITGB2 (0.66) | ITGB2ICAM1ITGAL | |
| SCHEMBL13817317 | 0.86 | ITGB2 (0.66) | ITGB2ICAM1ITGAL | |
| SCHEMBL5000918 | 0.85 | ITGB2 (0.75) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550494-B2 | Small molecules useful in the treatment of inflammatory disease | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-06-23 | — | — | US | disclosed |
| US-7550494-B2 | Small molecules useful in the treatment of inflammatory disease | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-06-23 | — | — | US | disclosed |
| EP-1216247-B1 | IMIDAZOIMIDAZOLES AND TRIAZOLES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMA (US) | 2008-11-05 | — | — | EP | disclosed |