Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 20/20 | 1.00 |
| ▸ | ICAM1 | P05362 | 20/20 | 1.00 |
| ▸ | ITGAL | P20701 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13816990 | 1.00 | ITGB2 (1.00) | ITGB2ICAM1ITGAL | |
| SCHEMBL4017369 | 0.92 | ITGB2 (0.85) | ITGB2ICAM1ITGAL | |
| SCHEMBL4017365 | 0.92 | ITGB2 (0.85) | ITGB2ICAM1ITGAL | |
| SCHEMBL13817169 | 0.91 | ITGB2 (0.84) | ITGB2ICAM1ITGAL | |
| SCHEMBL13817166 | 0.91 | ITGB2 (0.84) | ITGB2ICAM1ITGAL | |
| SCHEMBL13817161 | 0.89 | ITGB2 (0.81) | ITGB2ICAM1ITGAL | |
| SCHEMBL13817107 | 0.89 | ITGB2 (0.81) | ITGB2ICAM1ITGAL | |
| SCHEMBL13817194 | 0.89 | ITGB2 (0.84) | ITGB2ICAM1ITGAL | |
| SCHEMBL13817158 | 0.89 | ITGB2 (0.79) | ITGB2ICAM1ITGAL | |
| SCHEMBL13817329 | 0.89 | ITGB2 (1.00) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550494-B2 | Small molecules useful in the treatment of inflammatory disease | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-06-23 | — | — | US | disclosed |
| US-7550494-B2 | Small molecules useful in the treatment of inflammatory disease | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-06-23 | — | — | US | disclosed |
| EP-1216247-B1 | IMIDAZOIMIDAZOLES AND TRIAZOLES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMA (US) | 2008-11-05 | — | — | EP | disclosed |