Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 8/20 | 0.48 |
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27249711 | 0.84 | NR2E1 (0.56) | HPGDTSHRESR2RAB9ANPC1 | |
| SCHEMBL15649920 | 0.83 | SMN1; SMN2 (0.50) | HPGDTSHRESR2RAB9ANPC1 | |
| SCHEMBL2214941 | 0.83 | HPGD (0.50) | HPGDTSHRESR2RAB9ANPC1 | |
| SCHEMBL17076827 | 0.81 | HPGD (0.48) | HPGDTSHRESR2RAB9ANPC1 | |
| SCHEMBL17473523 | 0.75 | SMN1; SMN2 (0.48) | HPGDTSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL12844927 | 0.73 | SMN1; SMN2 (0.60) | HPGDTSHRESR2RAB9ANPC1 | |
| SCHEMBL14930399 | 0.72 | SMN1; SMN2 (0.51) | HPGDRAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL18483472 | 0.71 | KMT2A (0.67) | TSHRRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL18748599 | 0.71 | SMN1; SMN2 (0.53) | HPGDTSHRESR2RAB9ANPC1 | |
| SCHEMBL14912963 | 0.71 | SMN1; SMN2 (0.47) | HPGDTSHRRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541459-B2 | Method of producing amide compound | FUJIFILM CORPORATION (JP) | 2009-06-02 | — | — | US | disclosed |
| US-7541459-B2 | Method of producing amide compound | FUJIFILM CORPORATION (JP) | 2009-06-02 | — | — | US | disclosed |