SCHEMBL13818403

SCHEMBL13818403

c1ccc(-c2nc3cnccc3nc2-c2cc(-c3nc4ccncc4nc3-c3ccccc3)cc(-c3nc4ccncc4nc3-c3ccccc3)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.49
L3MBTL1 Q9Y468 5/20 0.49
ALDH1A1 P00352 5/20 0.49
KMT2A Q03164 2/20 0.49
ATM Q13315 2/20 0.49
TLR9 Q9NR96 1/20 0.49
MAPK10 P53779 1/20 0.47
MAPK14 Q16539 1/20 0.47
GAA P10253 3/20 0.47
LMNA P02545 3/20 0.47
TDP1 Q9NUW8 3/20 0.47
MEN1 O00255 1/20 0.47
DHODH Q02127 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
NPC1 O15118 1/20 0.45
HPGD P15428 1/20 0.45
RAB9A P51151 1/20 0.45
MAPT P10636 1/20 0.45
CSNK2A2 P19784 1/20 0.44
CSNK2B P67870 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13357728 0.94 KDM4E (0.52) KDM4EL3MBTL1ALDH1A1KMT2AATM
SCHEMBL13019839 0.84 TDP1 (0.71) KDM4EL3MBTL1ALDH1A1KMT2AATM
SCHEMBL1478550 0.82 KDM4E (0.65) KDM4EL3MBTL1ALDH1A1KMT2AATM
SCHEMBL8191361 0.81 CYP2A6 (0.54) KDM4EALDH1A1LMNASMN1; SMN2HPGD
SCHEMBL1352384 0.80 CYP2A6 (0.53) KDM4EL3MBTL1ALDH1A1KMT2AATM
SCHEMBL1352022 0.80 CYP2A6 (0.53) KDM4EL3MBTL1ALDH1A1KMT2AATM
SCHEMBL13820013 0.77 CYP11B1 (0.53) KDM4EL3MBTL1ALDH1A1KMT2AGAA
SCHEMBL24590011 0.77 MAPK14 (0.65) KDM4EL3MBTL1ALDH1A1KMT2AATM
SCHEMBL13726446 0.76 MAPK14 (0.64) KDM4EL3MBTL1ALDH1A1KMT2AATM
SCHEMBL13819929 0.76 MAPK14 (0.59) KDM4EL3MBTL1ALDH1A1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7547912-B2 Photoelectric conversion layer, photoelectric conversion device and imaging device, and method for applying electric field thereto FUJIFILM CORPORATION (JP) 2009-06-16 US disclosed
US-7547912-B2 Photoelectric conversion layer, photoelectric conversion device and imaging device, and method for applying electric field thereto FUJIFILM CORPORATION (JP) 2009-06-16 US disclosed
US-20070044829-A1 Photoelectric conversion layer, photoelectric conversion device and imaging device, and method for applying electric field thereto FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070044829-A1 Photoelectric conversion layer, photoelectric conversion device and imaging device, and method for applying electric field thereto FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed