Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.65 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 7/20 | 0.51 |
| ▸ | USP2 | O75604 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | BAP1 | Q92560 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GALK1 | P51570 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13198016 | 0.92 | MAPK9 (0.77) | MAPK9MAPK10LMNAUSP2TSHR | |
| SCHEMBL1518774 | 0.79 | MAPK9 (1.00) | MAPK9MAPK10LMNAUSP2TSHR | |
| SCHEMBL2425364 | 0.77 | MAPK9 (0.80) | MAPK9MAPK10LMNAUSP2TSHR | |
| SCHEMBL2422218 | 0.76 | MAPK9 (0.80) | MAPK9MAPK10LMNAUSP2TSHR | |
| SCHEMBL4204314 | 0.74 | MAPK9 (0.73) | MAPK9MAPK10LMNAUSP2TSHR | |
| SCHEMBL2419722 | 0.74 | MAPK9 (0.77) | MAPK9MAPK10LMNAUSP2TSHR | |
| SCHEMBL2428102 | 0.73 | MAPK9 (0.73) | MAPK9MAPK10LMNAUSP2TSHR | |
| SCHEMBL2419679 | 0.73 | MAPK9 (0.72) | MAPK9MAPK10LMNAUSP2TSHR | |
| SCHEMBL2425344 | 0.73 | MAPK9 (0.75) | MAPK9MAPK10LMNAUSP2TSHR | |
| SCHEMBL6431760 | 0.72 | MAPK9 (0.71) | MAPK9MAPK10LMNAUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541376-B2 | 1H-indazole compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-02 | — | — | US | disclosed |