Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 10/20 | 0.55 |
| ▸ | RAF1 | P04049 | 7/20 | 0.40 |
| ▸ | BRAF | P15056 | 5/20 | 0.40 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4095557 | 0.92 | BTK (0.55) | BTKRAF1BRAFSYK | |
| SCHEMBL4090528 | 0.91 | BTK (0.65) | BTKSYK | |
| SCHEMBL4091766 | 0.90 | BTK (0.58) | BTKRAF1BRAFSYK | |
| SCHEMBL4081255 | 0.87 | BTK (0.55) | BTKRAF1BRAFSYK | |
| SCHEMBL4090445 | 0.85 | BTK (0.54) | BTKRAF1BRAFSYK | |
| SCHEMBL4095483 | 0.85 | BTK (0.65) | BTK | |
| SCHEMBL4086089 | 0.84 | BTK (0.52) | BTKSYK | |
| SCHEMBL13771312 | 0.84 | BTK (0.55) | BTKRAF1BRAFSYK | |
| SCHEMBL4086761 | 0.83 | BTK (0.54) | BTKRAF1BRAFSYK | |
| SCHEMBL4095844 | 0.83 | BTK (0.51) | BTKSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009077334-A1 | NOVEL IMIDAZO[1,2-A]PYRIDINE AND IMIDAZO[1,2-B]PYRIDAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-06-25 | — | — | WO | disclosed |