Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3854614 | 0.85 | KMT2A (0.63) | KMT2AMEN1HDAC3HDAC1HDAC2 | |
| SCHEMBL10898099 | 0.84 | KMT2A (0.61) | KMT2AMEN1HDAC3HDAC1HDAC2 | |
| SCHEMBL29038563 | 0.84 | TSHR (0.60) | HDAC3HDAC1HDAC2TSHRL3MBTL1 | |
| SCHEMBL22373757 | 0.84 | TSHR (0.63) | KMT2AMEN1TSHRL3MBTL1GLA | |
| SCHEMBL5553293 | 0.80 | KMT2A (0.66) | KMT2AMEN1HDAC3HDAC1HDAC2 | |
| SCHEMBL29708225 | 0.79 | HDAC3 (0.74) | KMT2AMEN1HDAC3HDAC1HDAC2 | |
| SCHEMBL3241002 | 0.79 | HDAC3 (0.74) | KMT2AMEN1HDAC3HDAC1HDAC2 | |
| SCHEMBL11300484 | 0.79 | TSHR (0.64) | KMT2AMEN1TSHRL3MBTL1GLA | |
| SCHEMBL10596421 | 0.79 | TSHR (0.52) | KMT2AMEN1TSHRL3MBTL1GLA | |
| SCHEMBL2128698 | 0.78 | HDAC3 (0.68) | KMT2AMEN1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2524958-B1 | LUBRICANT COMPOSITIONS CONTAINING A HETEROAROMATIC COMPOUND | AFTON CHEMICAL CORP (US) | 2021-07-07 | — | — | EP | disclosed |
| US-9090847-B2 | Lubricant compositions containing a heteroaromatic compound | AFTON CHEMICAL CORPORATION (US) | 2015-07-28 | — | — | US | disclosed |
| US-20120291737-A1 | LUBRICANT COMPOSITIONS CONTAINING A HETEROAROMATIC COMPOUND | AFTON CHEMICAL CORPORATION (US) | 2012-11-22 | — | — | US | disclosed |
| EP-2524958-A1 | Lubricant compositions containing a heteroaromatic compound | Afton Chemical Corporation (US) | 2012-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120291737-A1 | LUBRICANT COMPOSITIONS CONTAINING A HETEROAROMATIC COMPOUND | HRH3, TRIB1, HRH4 | KMT2A 1456/4885MEN1 1721/4885HDAC3 2964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.