Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 13/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13822692 | 1.00 | CCNT1 (0.35) | CCNT1CDK9MAPTCTSBACACB | |
| SCHEMBL13719661 | 0.87 | SMN1; SMN2 (0.35) | MAPTCTSBACACBMITFHTT | |
| SCHEMBL12517475 | 0.84 | MAP4K4 (0.47) | — | |
| SCHEMBL13720109 | 0.81 | ACACB (0.36) | MAPTACACB | |
| SCHEMBL12518915 | 0.81 | MAP4K4 (0.45) | ALDH1A1 | |
| SCHEMBL13719714 | 0.81 | SMN1; SMN2 (0.38) | CCNT1CDK9MAPTMITFHTT | |
| SCHEMBL12518775 | 0.80 | MAPT (0.50) | CCNT1CDK9MAPTSMN1; SMN2GPR119 | |
| SCHEMBL12518773 | 0.80 | PIM1 (0.45) | — | |
| SCHEMBL12517591 | 0.80 | MAPT (0.54) | CCNT1CDK9MAPTSMN1; SMN2GPR119 | |
| SCHEMBL13719960 | 0.78 | SMN1; SMN2 (0.36) | MAPTCTSBACACBMITFHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2524917-A1 | FUSED PYRIDINE DERIVATIVES | Xuanzhu Pharmaco., Ltd. (CN) | 2012-11-21 | — | — | EP | disclosed |